European Journal of Zoological Research
Abstract
Author(s): Ali Khodadadi, Hossein Nikpiran, Peyman Bijanzad2, Hamed Moomivand3 and Saeed Kahnamoie
Antimicrobial therapy is one of the important tools in reducing the economic losses in the poultry industry caused by
Escherichia coli infections (colibacillosis), but the abusive use of antibiotics is the cause of the high percentages of
resistance to antibiotics. At this moment there is no information available about the difference of antibiotic
resistance in broiler breeder and broiler farms. To asses susceptibility of Escherichia coli to antimicrobial drugs in
broiler breeder and broiler farms in East Azerbaijan, In vitro antibiotic activities of seven antibiotic substances
against the Escherichia coli were determined by the standard disk diffusion method in Mueller-Hinton agar.
Antibiograms in broiler breeder farms revealed that Fosbac (94.12%) has the highest sensitivity and it found to be
most effective followed by Florfenicole (76.47%), Enrofloxacin (35.29%), Trimethoprim-Sulfamethoxazole
(29.41%), Danofloxacin (23.54%), Difloxacin (17.65%) and Doxycyclin (10.34). On the other hand in broiler farms
again Fosbac (92.38%) was the most effective antibiotic followed by Florfenicole (45.71%), Enrofloxacin (16.19%),
Danofloxacin (9.52%), Trimethoprim-Sulfamethoxazole (5.72%), Doxycyclin (5.71) and Difloxacin (4.76%). These
findings confirm significant increase in the incidence of antimicrobial resistance in the E. coli isolates and the
abusive use of antibiotics can be the cause of the high percentages of resistance detected in East Azerbaijan
province. Also these findings indicate that antibiotic resistance in broiler farms is higher than broiler breeder farms
and it might be due to the fact that broiler breeder farms pay more attention to their farms and most of the time they
use antibiograms before using antibiotics.
