Our study was focused on the quantification and determination of the chemical composition of both aqueous and ethanolic extracts from dried leaves and stems of five Lebanese plants Astragalus coluteiodes, Astragalus angulosus, Euphorbia macroclada, Trigonella berythea and Anacyclus nigllifolius. In order to detect the presence of phenol, saponin, coumarin, tannin, alkaloid, flavonoid and volatile oil, a preliminary phytochemical screening has been done. The quantification of saponin, alkaloids, lipids, ash, elements contents and humidity has been done using the classical methods. The phytochemical screening showed that aqueous and ethanolic extracts from both the leaves and stems of the five studied plants contain polyphenol, flavonoid, tannin, saponin and terpenoid in different concentrations. On the other hand, our plants contain fewer amounts of some heavy metals (Fe, Cd, Mn, Cr and Cu). From our work, it can be concluded that both leaves and stems of the five plants contain good compounds that may be used in the prevention or treatment of some diseases.