Sebastiania chamaelea MUELL. ARG., a medicinal plant from the family of Euphorbiaceae has been selected based on its usage in the traditional, folklore and ethnobotanical importance. In this study, the antioxidant potential of different spray dried extracts of aerial parts of S. chamaelea herb was established. Total phenol content, Total flavonoid content, DPPH radical scavenging activity and reducing power assay of the extracts were determined. IC 50 value for free radical scavenging activity of hydro alcohol (Methanol: Water) and alcohol (Methanol) extracts were found to be 0.061 mg/ml and 0.062 mg/ml respectively. The EC 50 value for reducing power assay of hydro alcohol and methanol extracts were found to be 0.173 mg/ml and 0.190 mg/ml respectively.
