Tinea infections is the most common in the world. Tinea corporis and tinea craris is caused by Trichophyton rubram. Trichophyton mentagrofits and microspurm canis. Our goal is to comparative efficiency of Itraconazole and Griseofulvin in the treatment of tinea corporis and cruris. This study is a randomize double blind clinical trial that has done from 2009 up to 2010. 80 patients with tinea corporis and cruris devided in two group, 75 patients has reffered completely for visit. The first group was under the treatment with itraconazole 100 mg daily for 2 weeks and the same time with placebo second group with Griseofulvin 500mg by time for 4 weeks. Remission of lesions have cared in 1 st. 2nd, 3rd, 4th week after the treatment and six weeks after end of treatment frome the point of clinic/KOH smear then results was analysed. The remission of lesions with Itraconazole was more than Griseofalvin (P=0.02).This stady showed that itraconaole 100 mg daily has more effects than Griseofulvin.
