Beta vulgaris is a plant native to Mediterranean, the Atlantic coast of Europe, the Near East, and India belong to Amaranthaceae, Genus Beta, and Subfamily Betoideae. The aim of this study is to overview Chemistry and pharmacological effect of beta vulgaris .This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases up to 2016.Among 89 found articles, 54 articles were included. The search terms were “Beta vulgaris”, “therapeutic”, and “pharmacological”, "Chemistry". Various studies have shown that Beta vulgaris possess anti-inflammatory effect, antioxidant Properties, anti-stress effect, anti-Anxiety and anti-depressive effect, anti-cancer, antihypertensive effect, hydrophobic properties, anti-sterility effects. The result of this study have found various constituents of Beta vulgaris exhibit a variety of therapeutic effects with little or no associated toxicity. These results are very encouraging and indicate this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects. Clinical trials using Beta vulgaris for a variety of conditions should also be conducted.