Utilization of adventitious root sap of Musanga cecropioides for various health and nutritional purposes in humans and livestock have been reported by many traditional and rural dwellers in Uyo metropolis. The present study quantitatively investigated the bioactive and elemental composition and the antimicrobial activities of the sap for the purpose of establishing its medicinal properties. The sap was shown to contain medicinally significant amount of tannins and saponins, with amount of oxalate that was quite below toxic dose. An appreciable amount of potassium (6.389±0342mg/L), calcium (34.330±2.273mg/L), magnesium (5.344±0.115mg/L) and phosphorus (12.150±1.737mg/L), with a low level of sodium (0.109±0.022mg/L) were found in the sap. Very low amount of heavy metals were demonstrated in the sap. The root sap of Musanga cecropioides produced significant antimicrobial activities against both gram negative and gram positive bacterial and significant antifungal activity.
