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Carboxymethyl cellulose film-implant with silver nanoparticles for the treatment of burns, with different etiology | Abstract
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European Journal of Applied Engineering and Scientific Research

Abstract

Carboxymethyl cellulose film-implant with silver nanoparticles for the treatment of burns, with different etiology

Author(s): Kh.E- Yunusov

Silver nanoparticles inhibit the activity of the enzyme providing oxygen exchange in protozoa, such as pathogenic bacteria, viruses, and fungi (about 700 species of pathogenic flora and fauna) [1]. The transition from the ionic Ag+ form to metallic nanoclusters makes it possible to reduce silver’s toxicity to cells of higher organisms without suppression of the antimicrobial activity against pathogenic microflora. Silver nanoparticles, especially stabilized ones, have greater stability and prolonged action [2]. Sodium carboxymethylcellulose (Na-CMC) - a water - soluble film forming biodegradable polymer widely used in the production of oral pharmaceuticals and drugs for external use primarily to increase the viscosities of ointments, in the production of pastes as hydrogel bases, and in the production of drugs for parenteral use - is of high interest as a stabilizer of silver nanoparticles. In addition,