A number of studies have reported that high free fatty acid (FFA) availability induces decreases carbohydrate oxidation and delay in onset of fatigue. The study objective was to determine whether L-carnitine supplementation combined to heparin injection affect glucose metabolism and aerobic capacity. A total 34 untrained young males divided to experimental and control by randomly. All participants completed a cycling test according to according to Astrand submaximal ergometry protocol on two separate occasions. 1) Exercise test without any supplementation in two groups. 2) Exercise test after heparin infusion + L-carnitine ingestion in experimental group and lactose supplementation in control group. A venous blood sample was immediately collected after each cycling test for measuring plasma glucose and Lactate concentration. A Sample T test was used to determine significant differences between the two groups. Maximum oxygen consumption (VO2max) was measured using a cycling test. Glucose concentration did not affect by L-carnitine-heparin supplementation in experimental group (p<0.05). In addition, this supplementation had not effect on circulating Lactate levels VO2max (p<0.05). These variables also did not affect by lactose supplementation in control group (p<0.05). Based on these data, it is concluded that carbohydrate metabolism determinatives or aerobic capacity doesn't affect by acute supplementation by L-carnitine combined to heparin injection.
