Cannabinoids, which are active components of the Cannabis sativa plant, were utilised as medicinal treatments for a range of ailments in traditional medicine for millennia before becoming stigmatised owing to their euphoric properties. After the discovery of the chemical structure and isolation of various substances in the second half of the nineteenth century, and the subsequent development of cannabinoid-based drugs that have been FDA approved primarily to treat chemotherapy-induced nausea, insomnia, and appetite, epilepsy, spasticity, and pain management, phyto-cannabinoids were re-evaluated.
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