The use of environmentally benign materials such as plant extract for the synthesis of silver nanoparticles (AgNPs) offers numerous benefits of eco-friendliness and compatibility for pharmaceutical and other biomedical applications. In this study, we have used Momordica charantia leaf extract as a reducing agent for the synthesis of AgNPs. Characterization of the AgNPs was done by UV-Visible Spectroscopy, Transmission Electron Microscopy (TEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). An intense surface plasmon resonance band at 418 nm in the UV–visible spectrum clearly revealed the formation of AgNPs. SAED and XRD patterns confirmed the presence of highly crystalline and face-centered cubic structure AgNPs and they were generally found to be spherical in shape with variable size ranging from 10 to 50 nm, as evident by TEM. Phenolic compounds present in Momordica charantia leaf extract were mainly responsible for the reduction and the stabilization of AgNPs. The biosynthesized AgNPs exhibited a strong antibacterial activity against Kelbsilla pneumonia bacteria.
