Der Pharmacia Lettre
Abstract
Author(s): Baskar Lakshmanan, Papiya Mitra Mazumder, Dinakar Sasmal, Swastika Ganguly
A few 1-substituted imidazoles 1(a-d) and 2(a-d) have been synthesized and characterized on the
basis of elemental analysis, FT-IR, 1H-NMR, DART-MS spectral data. The synthesized
compounds were screened for their in vitro growth inhibiting activity against different strains of
bacteria and fungi viz., Staphylococcus aureus, Bacillus subtilis, Streptococcus faecalis,
Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Candida albicans, Aspergillus
niger and Penicillium chrysogenum (10 and 50�Ž�¼g/ml) and the results were compared with the
standard antibiotic Ciprofloxacin and ketoconazole (10�Ž�¼g/ml) using agar diffusion technique.
