The goals of treatment for UTIs are to relieve symptoms, eliminate the infection, prevent recurrence and prevent serious complications such as kidney damage and sepsis results due to improper treatment. Exploring unexplored aspect of wild plants for developing antibacterial drugs as novel attempt further investigation. Study aims to screen eleven wild medicinal plants possessing antibacterial activity against the clinical bacterial isolates from urinary tract infection patients. The methanolic and ethanolic plant extract were analyzed by well diffusion assay and phytochemical characterization of the active ingredient were determined possessing antibacterial activity. Relative percent occurrence of E. coli was found to be maximum, followed by Klebsiella, Pseudomonas and Staphylococcus respectively. All the test pathogens were effectively controlled by the methanolic extracts of Acacia nilotica, Tagetus erectus, Thevatia peruviana, Thuja occidentalis and the ethanolic extracts of Acacia nilotica, Tagetus erectus, Murraya koenigii, Lawsonia inermis due to the higher levels of alkaloids, tannins and phenols. Plants possessing phenol, tannin and alkaloids show antibacterial activity. Screening of wild plants can be a novel approach for potential lead molecules and treatment of UTI. Determining exact component in these extract possessing antibacterial activity can be recommended for the alternative therapy for drug designing.
