Regarding to human beings, Aspergilli were isolated from all age groups but the majority of infection exists among the 20-40 years group but it was nearly equal and higher in farm workers than in farm owners and veterinarians. Aspergillus species was detected in sputum samples but in blood serum samples by using ELISA IgG. The zoonotic Importance of Aspergillosis as occupationally disease among poultry farm workers as well as the suggested hygienic measures were discussed to decrease its transmission to humans. A. Niger is commonly found as a saprophyte growing on dead leaves, stored grain, compost piles, and other decaying vegetation. The spores are widespread, and are often associated with organic materials and soil. Most of the fungi particularly A. niger, and A. flavus were also isolated from sputum of poultry-men working in such five farm in Mounofia Governorate.
