The plant Cassia fistula Linn. belonging to family leguminosae, known as Cassia in English, Amaltas in Hindi. The methanolic extract of plant pod showed the presence of glycoside, steroids, amino acids, flavanoids. The present study was focused to evaluate antipyretic activity of pod of Cassia fistula Linn. The methanolic extract showed antipyretic activity, which was significantly (P<0.05) higher than control rats. The antipyretic activity of Cassia fistula Linn. is due to individual or combined action of bioactive constituent present in it. The present finding results provide scientific evidence of ethanobotanical use of the plant of Cassia fistula Linn.