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Antiplasmodial isoprenylated flavonoids from the stem bark of Erythrina ovalifolia Roxb | Abstract
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Abstract

Antiplasmodial isoprenylated flavonoids from the stem bark of Erythrina ovalifolia Roxb

Author(s): Tjitjik Srie Tjahjandarie and Mulyadi Tanjung

Fourisoprenylated flavonoid derivatives,erythrisenegalone (1), alpinumisoflavone (2), phaseollidin(3), and sandwicensin (4) were isolated from the stem bark of ErythrinaovalifoliaRoxbTheir structures were elucidated on the basis of spectroscopic analyses. Compounds 1–4 were evaluated for their antiplasmodial properties against Plasmodium falciparum, showing their IC50 were 1.69, 1.98, 1.66, and 1.83μg/mL, respectively.