An antioxidant is a compound that inhibits or delays the oxidation of substrates even if the compound is present in a significantly lower concentration than the oxidized substrate. Antioxidants that scavenge reactive oxygen species (ROS) and reactive nitrogen species (RNS) may be of major importance in preventing the onset and/or the progression of oxidative pathologies and provide protection to foods. Antioxidant secondary metabolites from in vitro cultures include three classes: Polyphenols (Anthocyanins, Flavonoids, Flavone, Lithospermic B),Isoprenoids (carotenoidLycopene, monoterpene, Xantophylls), Other structures:Tocopherols (vit E), Betalanins: Kinobeon A ,Vitamin B6 ,Ascorbate , Reduced glutathione, Superoxide dismutase(SOD),Catalase ,Selenium ,Manganese. In this paper, structure and the list of some medicinal plants with these compounds were reviewed.