Origanum vulgar belongs to the plant family of Asteraceae , native to temperate Asia, but naturalized in many countries including scattered parts of North America (11, 12). It is an annual short-day plant. Its stem is erect brownish or violet brown. The aim of this study was to overview its Antioxidant, anticancer, antimicrobial effect. This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases .The initial search strategy identified about 150references. In this study,65studies was accepted for further screening and met all our inclusion criteria [in English, full text, therapeutic effects of Origanum vulgare and dated mainly from the year 2009 to 2016.The search terms were “Artemisia annua”, “therapeutic properties”, “pharmacological effects”. It is commonly used for its Antioxidant , Bio-efficacy , Antiproliferative , Radioprotective, Antibacterial and anticancer , Anti-proliferative, Colon cancer, Anti-thrombin activity , Antioxidant, Antibacterial, and Cytotoxic properties, Enterotoxin, Antibacterial, Antimicrobial , Bioactivity, The cytotoxic effect , Cell damage properties, Diabetes properties, Genotoxicity properties, Anticancer and antioxidant properties, Liver toxicity properties, Oxidative lung damage properties, Antioxidant and antiviral activities, Hepatoprotective effect, Antiurolithic activity, Antimelanogenesis properties, Low-density lipoproteins, Inhibitory activity, Antibacterial and antioxidant properties, Radical scavengers properties . It was said to be good for cancer treatment. Origanum vulgareis used for the treatment of various diseases such as diabetes, heart diseases, arthritis and eczema and possess lots of effects as antibacterial, antioxidant, Antimicrobial , Antibacterial effects. In this study, anti-cancer and Anti-inflammatory properties of this plant are presented using published articles in scientific sites. Besides, it was said to be good for cancer treatment.
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