A study was conducted on an Ethnomedicine namely Pajanelia longifolia (Willd.) K. Schum, which is commonly used in skin disease in the Dakshina Kannada District of Karnataka State. The antibacterial and antioxidant potential of the bark of the plant has been carried out by using various extracts. The estimation of polyphenols, proteins, carbohydrates and tannins were also carried out. The plant root powder showed remarkable degree of antioxidant activity and antibacterial properties against Staphylococcus aureus, Escherichia coli, Lactobacillus fermentum and Bacillus spp.
