Although the present survival and availability of synthetic drugs for the treatment of various diseases, these medications are neither cheap nor completely effective. Furthermore, the long-term utilization of synthetic drugs may cause adverse effects, despite the fact that those medications provided from natural sources are more affordable and shown lesser adverse effects. The existing belief is oxidative stress plays a considerable role in the pathogenesis of a range of diseases and its complications. Our aims to find and evaluate the combination of strong antioxidants are positively work various disease and its complications. They exhibited strong anti oxidant activity DPPH(2, 2-Diphenyl-1-picrylhydrazyl) scavenging activity with IC50 value of 66.35±1.2 and51.5±2 μg/ml for Ascorbic acid and Aqueous Ethanolic Extract of Ageratum albidum leaves (AEEAA) respectively. They strongest anti oxidant activity have Aqueous Ethanolic Extract due to may be presence of flavonoids and phenols.