Der Pharmacia Lettre
Abstract
Author(s): Lisa Mary Mani, Sankar.C, Dilip. C, A.K Azeem, Divya Raj, Lintu Mathew, Abdul Bari M Mambra, Laigy Ann George, Jayaprakash A.P, Hogan Alex, Sreethu.K.S, Divya .S Thampi
To study the antimicrobial activity of Lantana Camara. Linn, and its isolated constituent and
also to find phytochemical constituents. The leaves of the plant under study was collected and
processed for hot extraction by soxhlet apparatus using ethanol and water as solvents. From the
qualitative analysis phytochemical evaluation revealed the presence of flavanoids, triterpenoids,
alkaloids, and volatile oils. Its antimicrobial sensitivity testing was detected by measuring the
zone of inhibition of different bacterial culture using disc plate method. Alcohol extract showed
more antibacterial activity than water extract, against E.coli Bacillus aureus, Pseudomonas
auroginosa, and Staphylococcus aureus. Among them these extracts have more antimicrobial
activity towards E.coli. When compared with the standard gentamycin, the extract showed
comparable antimicrobial activities. Phytochemical studies indicates that the presence of
flavanoids, volatile oils, triterpenoids, alkaloids, and carbohydrates. Presence of triterpenoids
may be responsible for the antibacterial activity. Large scale production of active constituents of
Lantana Camara. Linn would be an advantageous for natural, herbal antimicrobial agents.
