The plants represent an enormous reservoir of potential antimicrobial compounds that could be useful as an alternative to synthetic microbicides and are being used to develop drugs. In the present study, antimicrobial activity of various leaf extracts of Ricinus communis was performed by Disc diffusion method. The results of antimicrobial activity revealed that all the extracts showed good inhibitory activity against all the tested microbes. Ethyl acetate and methanol extracts of leaves showed comparatively better activity than petroleum ether extract. These findings established the potential of Ricinus communis L. as an effective antimicrobial agent. Thus they can be used in the treatment of infectious diseases caused by microbes. Further studies are necessary to substantiate our findings and medicinal benefits in chemotherapy among humans.