In present scenario natural indicators are more efficiently prepared as it has several advantages over synthetic indicator. Clitoria ternatea Linn is a species of the genus clitoria , belonging to family Fabaceae. In the present research work natural indicator of Clitoria ternatea flower extract were prepared and it is use as an indicator in various acid base titration. The equivalence points obtained by the flower extract compared with the equivalence point obtained by standard indicators. In case of weak acid and weak base titration, the results obtained by the flower extract matched with the results obtained by mixed indicator and also the prepared methanolic flower extract were tested for antimicrobial activity against Staphylococcus aureus and showed significant anti-microbial activity. This natural indicator was found to be very effective, useful , cost effective, simple and accurate for the said acid base titration.
