Heliotropium strigosum Willd. (Chitiphal) is a medicinally important herb belongs to the Boraginaceae family. Traditionally, this plant was used in the medication therapy of various ailments in different populations of the world. The main objective of the current research was to probe the antiglycation and insecticidal potential of this plant. In the present study, the dichloromethane and methanol crude extracts of whole plant of H. strigosum were screened to explore the antiglycation and insecticidal potential of this plant by using bovine serum albumin (BSA)- methylglyoxal assay and contact toxicity method respectively. The results showed that the methanolic extract showed weak antiglycation activity at the concentration of 2mg/ml with the inhibition of 52.93% and IC50 of 1.8 ± 0.15 while the dichloromethane extract found to be inactive and showed 47.30% inhibition at the same concentration. On the other hand, the dichloromethane crude extract demonstrated moderate insecticidal activity against Rhozopertha dominica with 40% inhibition and low activity with 20% inhibition against Sitophilus oryzae respectively while the methanol extract exhibited no significant activity against all the tested insects. The presence of various groups of secondary metabolites such as saponins, flavonoids and tannins were also confirmed by different phytochemical tests. On viewing the above contributions, the researchers come to know that from the isolation and purification of valuable phytoconstituents of this plant by using advanced scientific methodologies must be helpful in the preparation of therapeutic agents of desired interest in the world of drug discovery.
