Cuscuta reflexa Roxb. is obligate angiospermic parasite belong to family Convolvulaceae shows worldwide distribution. Present attempt has been made to study the antifungal properties of C. reflexa Roxb. For that, aqueous, ethanol, methanol, butanol and acetone extract of C. reflexa Roxb. stem examined against the test fungi viz. Fusarium sp., Penicillium sp., Aspergillus sp., Rhizopus sp., using disc diffusion method. Butanol, ethanol and aqueous extracts of C. reflexa Roxb. were effective against the Fusarium sp., Aspergillus sp., and Penicillium sp. but acetone and methanol extracts did not show any antifungal activity. It is interesting to note that Rhizopus sp. do not respond any extract.