The bio-materials of four marine mangrove medicinal plants viz., Aegiceras Corniculatum (AGC), Excoecaria agallocha (EA) Rahizophora Mucronata (RM) and Xylocarpus Granatum (XG), are extracted with hexane, methanol and dichloromethane. These extracts are submitted to the antifungal activity towards the strains: C.albicans NCIM 3471, C.albicans NCIM 3557, C.neoformans, NCIM 3452, C.glabrata, NCYC 388 and C.tropicalis, NCIM 3118 adopting Disc Diffusion method. It is found that XG MeOH extract is effective towards C.albicans NCIM 3471 strain while EA MeOH extract is effective towards the strains of C.albicans NCIM 3471, C.neoformans, NCIM 3452 and C.glabrata, NCYC 388. The AGC (MeOH) extract is found to be effective towards the strains: C.albicans NCIM 3557, C.albicans, NCIM 3471, C.neoformans, NCIM 3452, C.glabrata, NCYC 388 and C.tropicalis, NCIM 3118. With C.albicans, NCIM 3471 strain, the order of effectiveness of the extracts is: XG MeOH (2)> EA MeOH extract (16) = AGC (MeOH) extract (16) while with C.glabrata NCYC 388 strain the order is: XG MeOH (4) > AGC (MeOH) extract (32) > EA MeOH extract (64). With C.glabrata, NCYC 388 strain, the order of effectiveness is found to be: XG MeOH extract (4)> AGC (MeOH) extract (32) > EA MeOH extract (64) while with C.tropicalis, NCIM 3118 strain, only AGC (MeOH) extract (64) is found to be effective.
