Methanolic extract was prepared by using Leaves of Justica procumbens were tested for anti-diarrhoeal activity in different experimental animal models like castor oil induced, and Enterpooling test in rats. The toxicity values were established and 1/10th dose of the Methanolic extracts i.e. 300mg/kg and 500mg/kg were used for the entire study of anti diarrhoeal activities in rats. Antidiarrhoeal potential of extracts was evidenced by a significant reduction in faecal output in castor oil induced diarrhea and also a significant decrease in propulsive movement of gastrointestinal contents.
