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Antibiotic Susceptibility Profile of Bacteria spp. Isolated from Patients with Recurrent Cough in Cross River State, Nigeria | Abstract
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Abstract

Antibiotic Susceptibility Profile of Bacteria spp. Isolated from Patients with Recurrent Cough in Cross River State, Nigeria

Author(s): Akpan, M. M., Itah, A. Y., Akinjogunla, O. J. and Eshiet, U. M.

A study on bacterial species associated with recurrent cough was carried out using Standard Microbiological Techniques [SMT] and their susceptibility to some commonly available antibiotics was evaluated using Disc Diffusion method [DDM]. The prevalence of bacteria spp. isolated were as follows: Streptococcus pneumonia [20.4%], Streptococcus pyogenes [12.5%], Staphylococcus aureus [18.5%], Klebsiella pneumonia [20.5%], Escherichia coli [7.7%], Pseudomonas aeruginosa [6.6%], Haemophilus influenza [0.1%] and Corynebacterium diphtheria [13.7%]. The susceptibility patterns varied from one bacterial isolates to the other depending on the drug used. Streptococcus pneumoniae was 100% resistant to chloramphenicol, 95.6% resistant to cloxacillin and 84.8% resistant to tetracycline. Haemophilus influenzae was 100% resistant to ampicillin, erythromycin, cloxacillin and cotrimoxazole. 50% of the bacterial spp were resistant to the other antibiotics used except flouroquinolones. Klebsiella pneumoniae was 100% resistant to both tetracycline and chloramphenicol. Some of the bacteria exhibited multiple antibiotics resistance (MAR). However, this results show that the most efficacious antibiotics for the treatment of patients with recurrent cough were sparfloxacin and ciprofloxacin due to the high level of some resistance of the bacterial spp. associated with recurrent cough to other commercial sold drugs.