Achyranthes aspera Linn., a medicinal plant, belongs to the amaranthaceae family. In Ayurvedic system of medicine, the parts of this plant are used to treat various type of infectious diseases. Air shade dried and pulverized root material was extracted by using ethyl acetate, acetone and ethanol solvents at room temperature for twenty four hours. The solvents were collected under reduced pressure to get crude mass. The crude mass of all extracts were studied against Gram-positive and Gram-negative strains such as bacillus subtilis, staphylococcus aureus, salmonella typhimurium, escherichia coli, pseudomonas aeruginosa, salmonella abony by disc diffusion method. Among these extracts, ethanol extract exhibit significant antibacterial activity against most of the bacterial strains while ethyl acetate and acetone extracts demonstrated less activity. The results obtained in the present study reveals, the potency order of the such extracts, can be employed in the treatment of diseases caused by tested pathogenic bacterial strains.
