The present investigation deals with the antibacterial potentials phytochemical screening of the aqueous and organic solvents extracts from powdered leaves of solanum erianthum were tested against nine bacterial pathogens (E.coli, Proteus vulgaris, Proteus mirabilis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcous aureus, Salmonella typhi and Vibrio cholerae) by disc diffusion method. The results revealed that the ethyl acetate and chloroform extract shows high sensitivity to Vibrio cholerae, Salmonella typhi, and Serratia marcescens and less sensitivity and resistant to Pseudomonas aeruginosa. The phytochemical study revealed the presence of phenols, saponins, phytosterols, terpenoids, tannins and flavonoids.