Objective: The aim of the present study is to evaluate the antibacterial activity of the crude extracts of Paphia malabarica and Crassostrea gryphoides.
Methods: Crude extract of two Bivalvia was tested for inhibition of bacterial and fungal growth. Antimicrobial activity of the whole body of Paphia malabarica and Crassostrea gryphoides were tested against six bacterial strains and two fungal strains by disc diffusion method. The antimicrobial activity was measured accordingly based on the inhibition zone around the disc impregnated with Crude extract of gastrapods.
Results: The inhibition zone of (8 mm) was observed against Corynebacterium diphtheria and for fungi inhibition zone of (4 mm) was observed against Aspergillus niger in the crude methanol extract of Crassostrea gryphoides. In the case of Methanolic extracts of Paphia malabarica inhibition zone of (7 mm) was observed against Proteus vulgaris and for fungi inhibition zone of (4 mm) was observed against Malassezia furfur.
Conclusion: The Methanol crude extracts of Paphia malabarica and Crassostrea gryphoides show activity against both bacterial and fungal strains.