Acne is a common disorder of pilosebaceous follicle which mainly affects the teenagers up to 95% boys and 83% girls due to the hormonal changes. Modern acne therapy which includes comedolytic agents, antibiotics and various anti-inflammatory agents has many side effects due to prolonged therapy. Propionibacterium acnes and Staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. Excessive and prolonged use of antibiotics has lead to the development of resistance in acne causing bacteria, viz, Propionibacterium acne and Staphylococcus epidermidis. In the present study Saraca asoca were chosen based on their antibacterial activity against other Gram+ve and Gram-ve bacteria and was found to be effective against S.epidermidis. and P.acne and in present study physicochemical parameter, phytochemical analysis also determine.