Corallocarpus epigaeus Rottl.ex.Wild (Cucurbitaceae) is a prostrate or climbing monoecious plant Decotion of powder root has benefit in cases of chronic mucous enteritis and also used as anthelmintic The anthelmintic activity of the alcoholic and aqueous extracts of roots and rhizomes of Corallocarpus epigaeus was evaluated on adult earthworms – Lampito marutii, Eudrillus eugine, Eisenla foetida using Piperazine citrate as the reference standard. The extracts caused paralysis followed by death of the worms at all tested dose levels.