Nerium olender popularly known as ’Indian olender’ in India belongs to family Apocyanaceae. The objective of the present work was to identify the phytochemical constituents and also to evaluate the in vitro anthelmintic potency of the aqueous extract of Nerium olender flower using Indian earthworms (Pheretima posthumad). The various concentrations (15, 25, 50 & 100 mg/ml) of the aqueous extract were tested in vitro for anthelmintic potency by determination of time of paralysis and time of death of worm. Albendazole (15mg/ml) used as standard. The result of present study indicates Nerium olender potentiate to paralyze earthworm and also caused its death after some time. Thus, the present study demonstrates that Nerium olender is a potent anthelmintic.
