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Anthelmintic activity of Cassia auriculata L. extracts-In vitro study | Abstract
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Journal of Natural Product and Plant Resources

Abstract

Anthelmintic activity of Cassia auriculata L. extracts-In vitro study

Author(s): Sucheta A Gaikwad, Asha A. Kale, Balaso. G. Jadhav, Nirmala. R. Deshpande and Jyoti. P. Salvekar

Helminth infections are among the most common infections in humans, affecting a large population of the World. Use of herbal products as antimicrobial agents may provide the best alternative to the wide and injudicious use of synthetic antibiotics. Albendazole, the commercial anthelmintic drug is used as a standard reference and saline as control. As per WHO, only few drugs are frequently used in the treatment of these parasite infections In present study acetone, ethanol, methanol and quath extracts of Cassia auriculata L leaves were investigated for their anthelmintic activity against Ecinia foeitida. Three concentrations (5, 10, 20 mg/ml) of each extract were studied. This experiment involved the determination of time of paralysis and time of death of the worms. The gradual increased in a dose exhibited, a gradual increase in the activity. Quath and ethanol extracts displayed significant anthelmintic activity at highest concentration of 20 mg/ml. It was concluded from the experimental detail study that the plant revealed significant anthelmintic activity, therefore in vivo trials may be conducted for the use in livestock on scientific basis. The data were verified as statistically significant by using two way ANOVA at 1% level of significance (P-value < 0.01)