The use of immunostimulants as an alternative to the drugs, chemicals and antibiotics currently being used to control fish diseases in fish culture is attracting the attention of many researchers. In this context, many have focused on the use of medicinal plant and animal originated products as potential therapeutic measures for modulating the immune response to prevent and control fish diseases. The possible use of naturally available herbal extract such as Ocimum sanctum (Tulsi), Phyllanthus emblica (Amla), Azadirachta indica (Neem), Solanum trilobatum (Purple Fruited Pea Eggplant), Eclipta alba (Bhringraj), Zingiber officinale (Ginger), Echinacea (Purple coneflowers), Allium sativum (Garlic), Camellia sinensis (Green tea), Aloe vera, Cynodon dactylon (Bermuda Grass), Achyranthes aspera (Prickly Chaff Flower), Nyctanthes arbortristis (Night-flowering Jasmine), Tinospora cordifolia( Guduchi) and Picrorhiza kurooa( Kutki) and animal originated product like Chitin, chitosan and Fermented products of chicken egg (EF203) etc. has been discussed in this article. The aim of this paper is to review research currently being carried out on the herbal extracts and animal originated products that have been shown to modulate the immune system of fish.
