Angiogenesis is a normal process in the body characterized by the formation of new blood vessels from existing vasculature. Abnormal angiogenesis is a denominator of many diseases. The study evaluated the effect of different concentrations of Curcuma longa Linn. tea powder on the angiogenesis of 10-day old duck embryos. 500 mg of the C. longa tea powder was used in preparing the stock solution for 100ppm (T1), 200ppm (T2), and 300ppm (T3) experimental treatments. These are administered on the chorioallantoic membrane (CAM) of 10-day old duck embryos. After 48 hours, the secondary collaterals on the CAM are counted and compared with the control group and with each of the experimental groups. Results reveal that C. longa Linn. tea powder suppressed angiogenesis. The study found out that 200 ppm (T2) and 300 ppm (T3), significantly yielded anti-angiogenic effect. The control group (T0) and 100ppm (T1) ; and 100ppm (T1) and 200ppm (T2) have no significant difference which can be attributed to low amount and partial solubility of the phytochemicals in water. The synergistic effect of the phytochemicals present in C.longa powder, such as curcumin, quecetin, vitamin C, and vitamin E can affect various steps in angiogenesis. These were defined to be responsible for C. longa tea powder’s anti-angiogenic activity.
