Sentani lake at Jayapura is source of fresh water that most of its territory, located in Jayapura regency and natural waters that are teeming with activities of daily transport and various kinds of human activities. Water function of Sentani lake are for water needs, as well as the utilization of hydropower is used for irrigation in agriculture, fisheries and transport water and it also is a place carry a wide variety of contaminants, including in the form of organic and inorganic components. Inorganic components, is a dangerous heavy metals. Some heavy metals are dangerous and often pollute the water environment or water bodies are mainly mercury (Hg), lead (Pb), arsenite (As), copper (Cu), cadmium (Cd), chromium (Cr), zinc (Zn) and nickel (Ni). The first problem is high of erosion number 94.52 ton/hectare/year that the value higher than value of erosion tolerance number 25 ton/hectare/year. Second problem is chemical pollution indicated by high concentration Cu (0.020-0.054 mg/L). Those concentration are exceeds water quality standard that approve by government in Government Regulation No. 82 of 2001 about management water quality and water pollution control. There for is needed research and management for sustainable of Sentani Lake. The aims of this research are to analyze about the pollution load Sentani Lake, and to analyze the assimilation capacity Sentani Lake aquaculture. The research method are survey and experiment. Results from a research showed that the load of pollution from river is obtained as follow (each in ton/month) is Cu metal (ranges between 0.025 to 0.273). The assimilation capacity from lake is obtained as follow (in ton.month) is Cu (0.0613). The load of pollution are uper of the assimilation capacity.
