Gmelina arborea an important medicinal plant is one of the most widely cultivated species of the family Verbenaceae. It is highly valued from time immemorial because of its vast medicinal properties. The present article provides all necessary information regarding its phytochemical investigations, pharmacological actions and medicinal properties like anemia, anxiety, asthma, blood impurities, diarrhea, fever headaches, antioxidants, cardioprotective, antidiabetic, immunomodulatory, antipyretic and analgesic, antimicrobial, diuretic and many other activities. This review emphasizes on the detailed phytochemical components and medicinal uses along with pharmacological properties of different parts of Gmelina arborea.