Der Pharmacia Lettre

Abstract

An efficient synthesis of bis(indolyl) methanes under solvent free condition using Silica supported Chloroacetic Acid as reusable Catalyst

Author(s): D R. Chandama, M B. Deshmukha, A G. Mulika, P P. Patilb, D R. Patila, S D. Jagdalea, P V. Anbhulea, S A. Sankpala.

Silica supported chloroacetic acid has been utilized as an efficient and an environmentally friendly heterogeneous, reusable catalyst for the coupling of aromatic aldehyde and indole to produce bis(indolyl)methanes under solvent free condition. The significances of this protocol are mild reaction condition, excellent yield and simple work up procedure

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