With over 145 million affected individuals exhibiting multisystem symptoms, long COVID-19 syndrome continues to be a global public health concern. It is critical to attend to the needs of those affected by a syndrome that has a complex and diverse clinical presentation. To improve independence and quality of life, treatment solutions must take into account the elements that can have an impact and comprehend how they progress. Thus, the purpose of this research was to examine the impact of clinical and sociodemographic factors on existence and how they relate to symptoms of anxiety, depression, and asthenia. A cross-sectional descriptive study with observational data supplemented with an analytical investigation. The Activities of Daily Living Questionnaire (ADQL; p=0.002), age (p=0.042), and sex (p=0.034) all had significant univariate impacts on asthenia according to logistic regression. [overall health (p=0.014) and physical functioning (p<0.001)] and multivariate [physical functioning (p=0.04), adult age (p=0.01), and sex (p=0.019)] reduced mood [evolutionary time (p=0.028) and multivariate [time course (p=0.007), ADLQ (p=0.011), physical role (p=0.013), and overall health (p=0.001)] and anxiety [multivariate [physical functioning (p=0.034), age (p=0.011), time of evolution (p=0.001), and ADQL (p=0.011)] and physical functioning (p=0.046)
