The major purpose of this study was to examine the factors influencing the commercialization of nanotechnology in agricultural sector of Iran. The methodology used in this study involved a combination of descriptive and quantitative research. The total population for this study was 250 researchers in the field of nanotechnology in agriculture. Based on the perception of the respondents, about 65.75% of total common variance is explained by infrastructural, economic, informative, financial and cultural factors, where the majority of it has been explained by the infrastructural factor (24.29%).