Adiponectin, an adipocyte-specific protein, is associated with cardiovascular risk factors in diabetic patients. The study objective was to determine whether the serum adiponectin concentration was associated with lipid profile and body composition indexes in type 2 diabetic patients. For this purpose, Forty three obese sedentary (BMI≥30) with type 2 diabetic were enrolled to the study. Serum adiponectin, lipid profiles and anthropometrical indexes were measured in all patients after an overnight fasting. Pearson correlations method was used to determine the relations of adiponectin with other variables in obese subjects. Serum adiponectin levels were negatively correlated with triglyceride (TG), total cholesterol (TC), triglyceride to High Density Lipoprotein cholesterol (TG/HDL), visceral fat and abdominal circumference (p<0.05). There was no significant relationship between serum adiponectin with HDL and body mass index (p≥0.05). Our finding support this hypothesis that adiponectin is a appreciate predictor of cardiovascular risk factor in type 2 diabetic patients.
