Increased prevalence of Vancomycin-resistant Enterococci and their ability to transfer Vancomycin resistance genes to other bacteria have made them a subject of close scrutiny and intense investigation. This study was performed to determine the prevalence of Vancomycin-resistant Enterococci occurrence in children hospitalized in a Hospital in Tehran, Iran. During 12 months, we collected 780 stool specimens from 460 children hospitalized (age ranged from 1 to 180 months) in Mofid children's hospital, Tehran, Iran. Resistance to Vancomycin and other antibiotics were evaluated by Epsilometer test for isolated Enterococci. We observed 16.9% of Enterococci were resistant to Vancomycin. Enterococci were mostly resistant to the other antibiotics. In conclusion regarding to the increasing prevalence of Vancomycin-resistant Enterococci we suggest more studies to evaluate the resistance patterns of Enterococci to new antibiotics are being introduced to treat Enterococci infections nowadays.
