Arthritis is an acute or chronic inflammation of joint, often accompanied by pain, swelling and stiffness and resulting from infection, injury. Pain is the most common symptom and is associated with bad functional outcomes. Different kinds of arthritis are, widely spread among the population that make them a clinical problem. Among those osteoarthritis (OA) is a chronic, degenerative disorder of multifactorial aetiology, characterized by loss of articular cartilage and periarticular bone remodelling. OA causes joint pain, typically worse with weight bearing and activity, and stiffness after inactivity. There is no cure, and gradual, although slow, progression is most common. Whereas, Rheumatoid arthritis (RA) is an autoimmune disorder of unknown etiology characterized by symmetric, erosive synovitis and, in some cases, extraarticular involvement
