Introduction:Salvia officinalis L.is a plant growing and cultivated in some parts of Iran. The leaves of Salvia officinalis L.(Lamiaceae) are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic and diuretic as well as for functional gastrointestinal disorders. The aim of this study is to overview its therapeutic effects than its nutritive and industrial effects. This review article was carried out by searching studies in PubMed, Medline, Web of Science, and Iran Medex databases .The initial search strategy identified about 158 references. In this study,113studies was accepted for further screening and met all our inclusion criteria (in English, full text, therapeutic effects of Salvia officinalis L. and dated mainly from the year 1980 to 2015).The search terms were “Salvia officinalis L.”, “therapeutic properties”, pharmacological effects. It is commonly used for its antioxidant, antimicrobial, anticancer and anti- tumor, anti-stress and anti-anxiolytic and antidepressant, anti-Alzheimer, anti-cardiovascular diseases, memory improving and concentration, antiinflammatory. It was said to be good for insomnia and dyssomina. Salvia officinalis L.is widely used for therapeutic and non-therapeutic purposes that trigger its significant value. Various combinations and numerous medicinal properties of its extract, oil, and leaves demand further and more studies about the other useful and unknown properties of this multipurpose plant.
