Esenia fetida belongs to the family of lumbericidea and genus esenia. By red, purple or brown color, this worm is a kind of surface-born and essentially is waste-born and fertilizer- maker and lives in a wide range of climate type and it is active in all seasons. This article introduces eisenia fetida genus and its different applications in different areas. One of its most important applications is on feeding farmed fish, such as salmon, sturgeonet and the feeding of crustoceans like shrimp .It is has Ssuitable compounds and fatty acids and essential amino acids and high amount of omega-3.These characteristics distinguishe it from plant resources. The biological fertilizer that is made by earthworm is so useful in agriculture and residual waste and used as a fertilizer that has an important role in environmental protection. Finally we can say that this organism plays a crucial role in human life.