Wound is referred to the disruption of joined structure of the body caused by physical, chemical, and biological agents. Wound healing is a reconstructive process which takes place after damage to skin and soft tissues. After damage, inflammatory response is developed and subdermal cells begin to increase the production of collagen and then epithelial tissue is gradually reconstructed. In Iran traditional medicine, natural substances and medicinal plants are used to heal wounds. This study was conducted to review the most important medicinal plants used for wound healing in different provinces of Iran. The key words including wound healing and skin healing combined with the words medicinal plants, ethnobotany, and traditional medicine in Iran were used to search for in the databases Information Sciences Institute, PubMed, Scopus, Islamic World Science Citation Center, and Magiran. The findings of this study on 15 different regions of Iran indicated use of 67 medicinal plants for wound healing. In some regions Scrophulariastriata, Althaea officinalis, Nerium oleander L. andPlantago major L. were jointly used for wound healing. The medicinal plants reported in this study with their wound-healing property are some alternatives that could be used to develop herbal medicines effective on wound healing if complementary studies confirm their properties.
