Pain and inflammation are the main problems associated with different diseases in human communities. The currently available drugs including opioids and nonsteroidal anti-inflammatory drugs are helpful for all patients because of complications and side effects. Therefore, there is still the need for suitable analgesics and researchers are still studying in this regard. Medicinal plants are rich sources of bioactive substances and antioxidant, and could have analgesic uses. In this review study, analgesic medicinal plants were searched for. Medicinal plants and analgesics were used as key words. The findings indicated that Thymus vulgaris, Mentha pulegium, Ziziphora tenuior, Origanum vulgarel L.Spp, Satureja hortensis Linn, Salvia sclarea, Gundelia tournefortii L., Datura stramonium L., Carum copticum, Pistacia vera L., Coriandrium sativum, Cinnamomum zeylanicum,Artemisia herba-alba,Cuminum cyminum L., Elaeagnus angustifolia, Glycyrrhiza glabra, etc. are the most frequently used analgesics.