The objective of this tutorial review is to summarize some of the recent advances in a specific class of silica based multifunctional, heterogeneous catalysis. We are focusing on recent advances have led to the preparation of silica materials containing multiple, different functional groups that can be used as catalyst in organic synthesis. In this review we summarizes the recent used silica based catalyst in synthesis of different organic compounds their preparation, reaction schemes and procedures. This review will help the reader to understand the preparation and use of silica based catalyst in both theoretical and practical aspect.