A Convenient, rapid, simple and sensitive spectrophotometric method was developed and validated for the estimation of Vilazodone in bulk and pharmaceutical dosage form. The absorption maxima of the drug was found to be 240 nm. A linear response was observed in the range of 2-10 μg/ml with a regression coefficient of 0.999. The limit of detection and limit of quantitation for determination of Vilazodone were 0.29775μg/mL and 0.90228μg/mL respectively. Assay result was found to be 99.547 ±1.417. The percentage recovery was found to be 99.451 to 101.166. The numerical values for all validation parameters were within the limits as per the ICH (International Conference for Harmonization) guidelines. The developed method can be successfully applied to estimate the amount of Vilazodone in bulk and pharmaceutical dosage form without interference of exipients.
